A quasi-static test was carried out on five corroded RC frame beams in general atmospheric environment to analyze the influence of corrosion degree on hysteretic behavior. Based on the test results and the characteristic point parameters of the intact RC frame beam’s skeleton curve, the skeleton curve model of corroded RC frame beams was obtained. The cyclic degradation index βi based on hysteresis energy dissipation was introduced, and the hysteretic rules considering the basic strength degradation, post-capping strength degradation, unloading stiffness degradation and reloading stiffness degradation of corroded RC frame beams were proposed. Then, the restoring force model applied to corroded RC beams in general atmospheric environment was established. The comparison of the established restoring force model and the experimental hysteresis curves was performed. The results showed that the agreement was good, and the established restoring force model has high precision, which can better reveal the hysteretic behavior of corroded RC frame beams in general atmospheric environment. This study can provide a theoretical basis for the elasto-plastic analysis of corroded RC structures.