Pressure-cast-in-situ pile with spray-expanded frustum (PPSF) is a new type of pile developed by the authors, which has been widely used in practice due to its advantages of high bearing capacity and small deformation. To study the uplift bearing behavior of the PPSF, static load tests on the PPSF were carried out, and a three-dimensional finite element numerical calculation model for the uplift behavior of the PPSF was established. The reliability of the numerical calculation results was verified by using the static load test results of the PPSF. Based on the finite element numerical calculation results, the influence of factors, such as location, length-diameter ratio, diameter and frustum angle of expanded body with double-frustum, on the uplift bearing behavior of the PPSF was analyzed, and the failure mode of the PPSF and the interaction mechanism between expanded body with double-frustum and surrounding soils were clarified. The present research results can provide a reference for the establishment of deformation and bearing capacity calculation methods for the PPSF.