To explore the aerodynamic performance of high-speed trains with lift airfoil when passing by each other, a model of a CRH high-speed train with a three-car formation was taken as the research object, and the influence of different train intersecting speeds on the aerodynamic performance of high-speed trains with lift airfoil was discussed. The results show that the first airfoil in the direction of travel experiences more lift. The lift on the intersecting side is more susceptible to the non-intersecting side. As the velocity increases, the lift generated by the lift airfoil device also increases, but its amplification decreases. The middle car is less affected by the lateral force than the head car and tail car. With the increase of the speed, the maximum lateral force of the train gradually increases, but the amplification decreases. The intersecting side is obviously subjected to stronger trackside pressure than the non-intersecting side. With the increase of the distance from the centerline of the intersection, the change of pressure gradually decreases, but the overall trend remains consistent, showing an overall trend of “positive-negative-negative-positive”.