In the ceramic industry of China, a large mount of ceramic manufacturers have preselected and fine-grinded the raw materials before application in the production process. Hence, instead of breakage function, the dispersion ability of the slurry preparation equipment begins to play a key role to influence the ceramic slurry preparation efficiency. A new method to prepare the ceramic slurry with basket sand mill was promoted. In this work, α-Al2O3 powders for making ceramic slurry with basket sand mill was tested and analyzed. Laser particle analyzer and quanta 200 (FEI) were used to characterize the particle size distribution and microscopy, respectively. Furthermore, the authors studied the relationship among the particle size, grinding time, grinding bead diameter and stirrer speed experimentally and theoretically in the ceramic slurry (α-Al2O3) preparation process. The most drastic decrease of α-Al2O3 particle size was achieved by combination of ZrO2 grinding bead 2.2 mm with stirrer speed 2 500±10 r/min, and after the paricles were grinded for D50 reaches 1 μm.