The offset voltage of the OP directly influences the precision of the output voltage reference. To cancel the offset voltage, this paper adopts NPN to produce ΔVbe and designs a new feedback loop structure to produce a low voltage bandgap reference. The circuit is designed in SMIC 0.18 μm CMOS process. The temperature coefficient of this low voltage bandgap reference is 8 ppm/℃.The PSRR is -130 dB and the design output voltage is 0.5 V. The circuit has been successfully applied at a high speed, 16 bit ADC.