Construction monitoring is related to the safety of engineering structure.However，the research of construction monitoring is limited in building engineering involved with curved prestressed concrete box girder.Combined with engineering practice of a student activity center venue，the monitoring scheme was made and conducted to ensure the safety in erection process for the curved box girder subjected to large force at the same time，and to keep tracking the whole process of construction.Construction simulation for a butterfly-shaped roof structure of the venue was conducted based on Midas Gen finite element software.According to the actual construction process and the element birth and death technology，the stress and displacement changing tendency of the roof box girder were analyzed in detail.The results derived by the monitoring and simulation were compared.The results show that the simulation method was validated by the good agreement between the results obtained from monitoring and simulation.The stress and displacement of the box girder are in control，and the construction scheme can satisfy the need of construction.The research results provide important reference for the design and construction of the similar large profiled component in building engineering.