The Benchmark model of the floor response spectrum established by our study group was used to study the effect of different friction coefficients of the elastic slide bearing on the floor response spectrum. ETABS software was used to establish the finite element model of the seismic isolation structure， and the elastic slide bearing was arranged between the bottom of the ground floor column and the foundation. To make the floor response spectrum practical and representative， the 22 far-field vibrations recommended in ATC-63 were inputted to carry out the nonlinear time-distance analysis for the four friction coefficients of the base seismic isolation structure， respectively， and to study the effect of the friction coefficients of the elastic slide bearing on the floor response spectrum， which was compared with that of the friction coefficient of lead core rubber bearing seismic isolation. The results show that the friction coefficient affects the spectral value of the floor response spectrum but does not change the period of the peak value of the floor response spectrum and does not affect the spectral characteristics of the floor response spectrum； in the period of 0~6 s， the spectral value of the floor response spectrum of the four friction coefficients of elastic slide bearing structure in the paper is less than that of the lead core rubber bearing， which indicates that the seismic isolation performance of this structure of elastic slide bearing is better than that of the lead core rubber bearing.