Medical degradable β-TCP/WE43 composite was fabricated via multi-pass friction stir processing （MP-FSP）. The microstructure of the β-TCP/WE43 composite was characterized by metallography， scanning electron microscopy， and energy dispersive spectrometer， and the mechanical properties， corrosion resistance， and corrosion-wear performance of the composite were tested and analyzed. The results showed that， after three passes of friction stir processing （FSP）， β-TCP particles were well dispersed in the magnesium matrix， and the grains in the stirring zone were refined. MP-FSP can effectively improve the distribution of β-TCP particles in the magnesium matrix and refine the grains， thereby simultaneously enhancing the mechanical properties， corrosion resistance， and corrosion-wear resistance of the composite. These research findings can provide significant guidance for the development of biodegradable magnesium-based implants.