In order to investigate the effect of different disinfectants on the organic matter in drinking water, surface water from Huangpu River filtrated with MF membrane was studied. There was a significant difference among organic matter variations by chlorine, chloramine and UV. The oxidation of the organic matter in the water could be divided into highspeed and lowspeed stages with the variation of chlorine dosage from 1 mg/L to 4 mg/L. AOCNOX is the majority of the AOC composition in chloride water. AOC changes had a lesser extent and peak time lag than chlorine by chloramines disinfection. Irradiation by lowintensity UV (0.038 mW/cm2) had no effect on the AOC change. When AOC varied with the changes of UV dosage by highintensity（0.076 mW/cm2 and 0.153 mW/cm2), the changes of AOCP17 were consistent with AOC, and had no changes of AOCNOX.