There are many problems in the engineering application of concrete verticalhole hollow block masonry, for instance, poor thermal insulation, seepage and crack. To solve these problems, a new type of concrete horizontalhole hollow block masonry was developed. 9 groups with 54 compressive specimens of the new type masonry were tested, and the deformation characteristic and the failure mechanism of the new type block masonry were obtained. Based on the experiment results and by reference to the current national standards, a new compressive strength formula was proposed. The stressstrain formula and elasticity modulus computational method for the new block masonry were proposed by using a logarithmic function model. The significance of this paper is to implement the strength design for the new type masonry and provide a basis to stress analysis and finite element analysis under uniaxial compression behavior.