High-speed steel wires M42 and high strength steel strips X32 were welded on the band saw blade by using CO2 laser. The typical microstructure of welding joints，the distribution of elements,and the influence of different bonding technologies on welding joints microstructure and mechanical properties were studied by using metalloscope, electron microscope(SEM), microhardness meter and electron probe(EPMA). The results showed that isometric increased , dendrite decreased in the weld center and isometric near the side of M42 fusion boundary area became more fine with the increase of welding speed. The hardness of the welding joints in every bonding technology was higher than parent metal. Moreover, the hardness of the bond area near the side of M42 was higher than the welded zone's. When the welding power was 2 754 W and the welding speed was 14 m/min, the property of the welded joints was good, and the value of bending strength reached 112 MPa, which reached the requirements of double metal band saw blade welding.