Cu(OH)2 precursor was prepared with fast co-precipitation method by blending CuSO4·5H2O and NaOH solution at room temperature, and calcinating to obtain nano-CuO powder. The phase, particle size and morphology of nano-CuO were characterized by X-ray diffraction(XRD), laser particle sizer and scanning electron microscope(SEM). The catalysis of different products on NH4ClO4 (AP) decomposition was investigated by thermogravimetric analyzer(DTA-TG). The solution pH,calcination temperature and reaction time were investigated. The results show that the optimum reaction conditions are determined: solution pH is 14,calcination temperature is 350 ℃ and reaction time is 10 min. The exothermic peak of high temperature decreases by 90.1 ℃ compared with that of AP without CuO.