To evaluate the deformation and stress distribution of cement-concrete pavement under no-uniform temperature distribution along the depth direction, finite element analysis method was used in this research to simulate nonlinear temperature gradient load， and the nonlinear temperature distribution index was adopted to represent the degree of nonlinear distribution and to evaluate its effect on stress distribution. Models with different nonlinear temperature index parameters were constructed. The results indicate that, although the deformation caused by linear temperature gradient models was almost identical with that from nonlinear temperature gradient models, the linear temperature gradient models have overestimated bottom-up stresses and underestimated top-down stresses. When the nonlinear temperature gradient is negative, the influence of nonlinear temperature gradient on slab stress increases with the increase of slab thickness and elastic modulus. Besides, the effect of nonlinear temperature gradient is reduced with the increase of the base reaction module. What is more, based on the regression analysis of a large database, the formula of maximum tensile stress of the slab top was obtained.