To study the seismic performance of a new concrete filled tube-confined sandwich shear wall (CFT-SSW), cyclic loading tests were carried out on three CFT-SSW specimens with different depth-thickness ratios and one conventional concrete shear wall specimen for comparison. The load-carrying capacity, ductility, stiffness and their degradation, hysteretic and energy dissipation characteristics, and failure modes of the specimens were investigated and compared. Equations for prediction of the strength of CFT-SSWs were also proposed. The calculated strengths were in good agreement with the test results. The results show that CFT-SSWs exhibited both the high lateral stiffness and strength due to reinforced concrete shear walls and the superior ductility due to concrete filled tubes. The strength, ductility, and stiffness of CFT-SSW specimens were greater than those of the cast-in-situ concrete shear wall specimens. In addition, the depth-thickness ratio has only marginal effects on the seismic behavior of the CFT-SSWs within the test range of the current tests.