In order to investigate the vibration mitigation performance of the Tuned Liquid- Particle Damper (TL-PD) during earthquakes，a series of shaking table tests were conducted on a steel frame structure with different damping devices，including Tuned Liquid Damper (TLD)，Particle Damper (PD)，and TL-PD.During the testing，three ground motions were adopted as excitation inputs.Testing results show that the TL-PD has a good vibration suppression effect.The root-mean-square values of displacement and acceleration responses of the structure can be reduced by 63.2% and 50.5% at most，respectively.The TL-PD also shows a better robustness than that of the TLD，although the performance of the TL-PD is still influenced by the ground motion characteristics.Additionally，the TL-PD produced less noise than that of the PD in the tests.Based on empirical model，a mathematical model was developed to capture the behaviors of TL-PD in the preliminary design.