In order to master the regularities of dust movement with time and space in the screening workshop of asbestos concentrator and obtain the optimized parameters of dust removal by ventilation,screening workshop of No. 1 concentrator in Mangya Asbestos Mine was considered as the research background. Based on the theory of gas-solid two-phase flow,the discrete phase model (DPM) of computational fluid mechanics was used to simulate the dust concentration in screening workshop. By comparing with field measurement of dust concentration distribution,simulation results are essentially coincident with the measured data. The results indicate that the dust concentration near the screening equipment is higher,and the value decreases as the distance from the screening equipment increases. The dust concentration is lower under trap wall condition than the reflect,and the dust trapping effect is better. The dust settling effect is better when the inlet wind speed is about 0.6 m/s. When the exhaust dust cover is installed and the wind speed of main exhaust pipes is maintained at 14 m/s,the average dust-removal efficiency can reach 90%,and the asbestos fiber concentration can be controlled below 2.52 f/mL.