Real-time hybrid simulation is a new method of structural seismic test. A hybrid simulation test system is established, which includes the numerical simulation computer based on OpenSees finite element software, the target computer with time delay compensation function and the electro-hydraulic servo control system. Furthermore, the Simulink numerical simulation model is established in MATLAB, and an adaptive feedforward time-delay compensator based on displacement prediction is proposed. Finally, a single story and three span high-strength steel composite eccentrically braced steel frame structure was considered as the prototype, the single story steel frame with the eccentric brace was considered as the test sub-structure, and a real-time hybrid simulation test of a 1/2 scaled model was carried out. The experimental results show that the maximum time-delay compensation error and maximum amplitude error of the system increase with the increase of overall response peak acceleration of the model, but all of them are within the tolerance allowable range. At the same time, the hybrid simulation test system has good stability and accuracy, and can be used to test the seismic performance of the eccentrically braced frame as the test sub-structure.