The heat dissipation of lithium-ion battery pack has been an important factor affecting the battery life and traffic safety of electromobile. In order to explore the effect of different cooling pipeline design on the heat dissipation of lithium-ion battery pack， the surface temperature of a single lithium-ion battery under different conditions was studied by means of numerical calculation，and compared with the test results，the correctness of the simulation method was verified. Under the 27 ℃， the heat dissipation effects of eight different cooling structures were compared and analyzed， finding that the average temperature of 8th structure is 31.62 ℃ and the standard deviation is 0.83， which has the best cooling effect； the design of bidirectional flow， the inlet position ，the shunt situation of branch pipe， and the contact area between the cooling pipe and the battery pack will have different influences on the heat dissipation performance of the battery pack. Therefore， these factors should be taken into consideration in the design of the heat dissipation structure of lithium- ion battery pack.