The progressive collapse resistance of reinforced concrete plane frames removed post column was analyzed based on Pushdown method. The effect of the floor layers on the progressive collapse resistance capacity and the vierendeel action of the damage structure was investigated. At the same time，a method for calculating the system reliability of the reinforced concrete frame structure removed post column was proposed. By simulating static test of constrained beam，single-layer plane frame and multi-layer plane frame，the correctness of the finite element model based on OpenSees was verified. The 2，4，6 and 8-layer reinforced concrete frames were analyzed，and the Pushdown curve and the frame beam axis force curve were obtained. The bearing capacity enlargement coefficient was calculated by the Pushdown curve，and the correlation between the frame beams was set by the relative size of the strain of the frame beam. The results show that with the increase of storey，the average bearing capacity of single story decreases，and the probability of progressive collapse of structural system increases.