Based on the identification data of damping ratios measured from seven large cooling towers in domestic and taking the high-level water cooling tower as an object， four kinds of damping ratios （0.5%， 1%， 2% and 3% respectively) were set up to calculate the wind-induced responses by complete transient analysis. The calculated results were compared with these calculated under standard damping ratio （5%). On this basis， the influence of the damping ratio values on average and pulse responses of wind vibration of high-level water cooling tower was refined， the wind-induced vibration coefficients were calculated based on six different responses of wind vibration and three kinds of equivalent target under damping ratios. The influence law of different damping ratios， response targets and position on coefficients of wind vibration were summed up， and the damping ratio and meridian height were taken as an objective function of the wind vibration coefficients and the fitting formula was proposed by using the nonlinear least-square method. The main conclusion can be provided as references for damping ratio parameters of the high-level water cooling tower.