This study dealed with the applicability of Cohesive Zone Model (CZM) on the cold-mix foamed asphalt concrete by analyzing the results of both numerical simulation and laboratory tests comparatively and statistically. Based on CZM, 3D model specimens were built up for cold-mix foamed asphalt concrete by applying Matlab Convex Hull Algorithm and 3D ODEC Algorithm. Meanwhile, virtual splitting tests of the mixtures with different gradations were also carried out. The study indicates that the combination of Convex Hull and 3D ODEC Algorithm is able to simulate the coarse aggregates angularity. The simulated trend of strength-deformation curve obtained from the virtual splitting test is similar to the actual pattern, which suggests that the CZM-based 3D discrete element simulation can be applied to the design of cold-mix foamed asphalt concrete.