This paper studies the thermal responses of human subjects with different local cooling methods (radiation，conduction and convection) in hot-humid environments. Through experiments in the hot-humid environments in the experimental room，the data of subjective feelings were collected and the different effects generated by different local cooling methods on the local and overall thermal comfort were then analyzed. The obtained results showed that the time before subjects reached static-state condition differed with different local cooling: the time was less than 5 minutes with local convective cooling; the time was 10 minutes with conductive cooling and 20 minutes with local radiant cooling. In the reference condition，necks，legs and backs exerted large effects on overall subjective responses. When local cooling was applied，the local body parts which exerted large effects were those which were locally cooled directly，like upper-arms (local radiation)，lower-arms (local conduction) and heads (local convection). Moreover，according to the regression results of the thermal comfort vote at 26/28/30 ℃，it is the best to choose local radiant cooling when the ambient temperature is lower than 27.55 ℃，local convective cooling with the ambient temperature at 27.55-28.96 ℃，and local conductive cooling with the ambient temperature higher than 28.96 ℃，respectively.