In order to provide a simple and effective method for the fatigue performance analysis of bridge cable steel wires，according to the microstructure of the steel wire and statistical analysis results of relevant test data，a prediction model of steel wire fatigue crack growth rate is established，and the calculation method of model parameters is given. The fatigue crack growth rate in the stable growth region is obtained on the original steel wire by the variable load indentation method. The prediction model can better describe the data obtained from the test and the fatigue crack growth law of the steel wire in the near threshold region in the literature. On this basis，the fatigue life of new steel wire and corroded steel wire is calculated by the fracture mechanics method and compared with the test data. The results show that the corrosion will not affect the fatigue crack growth rate of the steel wire. The mechanical properties of the uncorroded steel wire can still be predicted by this method. The change of fatigue life of the corroded steel wire is attributed to the change of the initial flaw size. For new steel wire and slightly corroded steel wire，the equivalent initial flaw size method can be used to calculate the fatigue life；when the steel wire is corroded seriously，the total fatigue life is basically composed of the crack propagation life，and the initial flaw size is the true depth of rust pit. In view of the randomness of pit depth distribution，the maximum pit depth should be used to calculate the fatigue life of corroded steel wire.