The 304 stainless steel mesh was treated in a boiling solution containing 2 mol·L-1 nickel source for 120 s to obtain a self-supporting electrocatalyst（denoted SS/Ni-OH2M-120s） with excellent Oxygen Evolution Reaction（OER） performance. This self-supporting electrocatalyst facilitated industrialization and scale production. The overpotential of SS/Ni-OH2M-120s electrocatalyst obtained at the current density of 10 mA·cm-2 was 214 mV, which was about 127 mV lower than that of the blank 304 stainless steel mesh. After the constant potential polarization for 10 h at a current density of 20 mA·cm-2，the catalytic performance displayed no obvious change, indicating excellent stability. When SS/Ni-OH2M-120s anode was combined with the Pt mesh cathode（Pt-Mesh//SS/Ni-OH2M-120s） to make overall splitting water, a decomposition voltage of 1.61 V at the current density of 10 mA·cm-2 was achieved, which was 0.23 V lower than the commercial Pt-Mesh//IrO2 /SS.