Multiple alkynyl linear polyurethane resins（MAPU） were synthesized by polyaddition reaction using polyethylene adipate diethylene glycol（PADG），isophorone diisocyanate（IPDI） and 1，4-butynediol（BD）. The molecular structures of resins were characterized by Fourier transform infrared spectra and Raman spectra. Series of sulfhydryl-alkynyl UV curing polyurethane films（F-SAPU） and coatings（C-SAPU） were prepared using trimethylolpropane tris（3-mercaptopropionate）（TTMP） as a crosslinking agent. The synthetic and curing process of sulfhydryl-alkynyl UV curing resins were designed according to formulation parameters such as chain extension parameters，mass fraction of hard segment，curing parameters and photoinitiator parameters. The results showed that the tensile strength and elongation at break of F-SAPU were flexibly adjustable from 0.48 MPa to 5.32 MPa and 106% to 172%，respectively，and the glass transition temperature was in the range of -10.1 ℃ to 26.9 ℃ when changing the formulation parameters. In addition, the effect of mass fraction of hard segment on the performance of C-SAPU was explored. When mass fraction of hard segment was 45%，the coating had optimal performance.