This paper develops a novel continuous composite box girder bridge by combining ultra-high performance concrete (UHPC) with corrugated steel webs (CSWs) to overcome the weaknesses of traditional long-span prestressed concrete (PC) continuous girder bridges, such as excessive dead load and deflection at the mid-span, and cracking in the webs. The static and seismic performances of the CSWs-UHPC continuous composite box girder bridge are investigated. And its dynamic performance is compared to that of CSWs-normal concrete (NC) and PC continuous composite box girder bridges. The results reveal that: when compared, respectively, with the CSWs-NC composite box girder bridges and PC box girder bridges, the dead load of the proposed composite structure is reduced by 45% and 54%, the CSWs-UHPC composite continuous box girder bridge is highly durable, economically competitive throughout its life cycle. The static properties of the developed CSWs-UHPC composite structure meet the requirements of the specification. The ratio of the reasonable girder depth at the support to the mid-span（Hs /L） is 1/16 ~ 1/22, and the ratio of the reasonable girder depth at the mid-span to that at the support（Hm /Hs） is 1/1.5 ~ (-0.2+0.029L/Hs）. The CSWs-UHPC composite box girder bridge has a lower natural vibration frequency of transverse bending than the PC box girder bridge and a slightly greater natural vibration frequency of vertical bending than both the CSWs-NC composite box girder bridge and the PC box girder bridge. The lighter superstructure significantly reduces the inertia load, which makes the CSWs-UHPC composite box girder have excellent seismic performance. This new type of composite bridge can effectively address the issues previously mentioned for conventional long-span continuous bridges, as well as drastically minimize the seismic response. It will thus be a bridge type with competitive advantages over the traditional long-span continuous girder bridges.