This paper aims to investigate the general law of slope stability under pile foundation-induced loads and propose a calculation method of corresponding stability coefficients. Firstly, the finite element limit analysis method is introduced and verified by the case for the pile foundation in sloping ground. Next, some factors (e.g. lateral load atop the pile, cohesion, and the relative position between pile and slope) are normalized, and the calculation method of stability coefficients of the slope subjected to pile foundation-induced loads under various conditions is presented and expressed in tabular form. Then, the load impact factor is presented to characterize the effect of lateral loads atop piles on slope stability factors, while slope failure modes are explored, and the semi-experiential and semi-theoretical method of slope stability coefficient under loads induced by pile foundations are presented. Finally, the effect of lateral loads atop piles, the slope inclination, internal friction angle of soils, cohesion, and pile position on slope stability factors are discussed. The results show that the slope stability factors are positively correlated with internal friction angle and cohesion, and negatively correlated with lateral loads atop the pile. These above-mentioned analyses can provide references for bridge engineering design in the sloping ground, which are of certain theoretical and engineering application value.