Adopting the improved ASTM D1037 aging method， a series of artificial aging tests with 0， 3， and 6 times of dry-wet cycling were designed for larch laminate specimens to study the effect of long-term temperature and humidity alternation on the mechanical properties of the glulam. The influences of different times of dry-wet cycling on the macroscopic characterization of glulam， micromorphology， material density， and strength indexes of the compressive strength parallel to the grain， tensile strength parallel to the grain， bending strength， and shear strength of the rubber layer was analyzed. Results show that strength indexes decreased obviously after dry-wet cycling. With the increase in the number of dry-wet alternations， the decrease of the strength indexes of the specimen increases. After 6 times of dry-wet cycling， the decline amplitude of the compressive strength parallel to the grain， tensile strength parallel to the grain， bending strength， and shear strength of the rubber layer increased in turn， within 26.75%， 29.64%， 33.57%， and 40%， respectively. Compared with the initial crack， the effect of alternating dry and wet on the bending strength is more significant. The relationship between dry-wet alternation times and the strength can be fitted by a power function. Based on the corresponding relationship between the times of dry and wet alternations and time， time-varying models of larch glulam's compressive， tensile， bending， and shear strength of the rubber layer were established.