Aiming at the vibration frequency of automotive powertrain systems with problems such as multiple orders and narrow vibration bands of a single order， this paper proposes a multi-frequency line spectrum notch-filter vibration active control method based on the filtered-x least mean square algorithm. First， the method is based on the rotational speed signal to obtain the reference signals of multiple order vibration frequencies， and then the minimum mean square filter is used to calculate the offset signals of these order vibration frequencies. Secondly， based on the orthogonality of the vibration signals at different frequencies， the method further calculates the control signals with linear superposition to obtain the control signals of active suspension and eventually realizes the active control of multi-frequency line spectral vibration. Compared with the traditional filtered-x least-mean-square algorithm， this algorithm improves the acquisition of reference and control signals and thus has the advantages of less computation and faster convergence speed. Simulation and experimental results show that the proposed method reduces both the number of convergence by 81.25% and the steady-state error by 15%， respectively， compared with the traditional filtered-x least-mean-square algorithm. The maximum reduction is 34.01 dB under idling condition and 17.5 dB under WOT condition， respectively， compared with the traditional filtered-x least mean square algorithm.